The ubiquitin system, disease and drug discuvary Essay

The ubiquitin system, disease and drug discuvary - Essay Example Ub as a protein is heat stable in nature that formulate into a compact global structure. Ub can be seen in all cells and has the capability to exist in free form or with other cells in a complex nature. When existing with other cell it is attached to protein in a covalent state along the glycine at the C-terminal end of ubiquitin and lysine. However, single ubiquitin molecules can be seen conjugated with lysine of these protein.Ub has a role to play in many cell processes. For example, during the GI phase of mitosis,Ub is coupled to the cyclin protein, thus play an important role in regulating the cell cycle. The coupling of Ub is also seen in, DNA repair, the regulation of transcription, programming cell death and embryogenesis. It is a family of genes which encodes Ub and has fusion proteins as it translation products. The protein in Ub exists in a linear chain of amino acids. This linear chain of amino acids can degrade over time and it is called protein - turnover. The concentration of protein in the cell is determined by the balance between the synthesis and protein degradation in a cell. It has been understood by studies on protein turnover rate that some protein are short lived where as others live for long duration. Majority of protein in the cell is comprised of long lived protein. However, the main regulatory are the shorlived protein but they are abnormal proteins. The short-lived protein are easily prone to degradation because they get partially unfold. The Ub by regulating degradation of certain protein regulate the protein turnover in a cell. This kind of regulatory action is necessary in a cell. The regulating protein degradation has the ability to avoid a protein which regulates other necessary function in a cell. This kind of control is necessary in a cell as the disposal of this kind of regulatory protein helps in the cessation of processing of the regulatory protein. Inactivation of protein is also performed by

Tourism system Essay Example | Topics and Well Written Essays - 2000 words

Tourism system - Essay Example A large amount national income comes from the tourism industry. Such vast amounts of information and data have to be stored and processed and should be distributed to the customers as efficiently as possible. Information technology plays a very important role in the tourism industry because through the use of information technology, several devices can be implemented which are used to store large amounts of information. Tourism industry was never a very renowned industry and people were not very interested in tourism industry. IT was only recently due to the technical advancements in technology. The advancements in Information Technology resulted in both the quantitative and the qualitative aspects of the economy of a nation and also advancements in the tourism department consequently fueling and sustaining an impressive growth rate over the years (Franke, 2003). This brings into focus the role of IT in tourism education geared at nurturing the necessary skills in potential managers in the industry to make the industry influential and effective. The benefits of implementing Information Technology in tourism industry can only be observed through the development in the tourism industry all over the world. Information Technology when applied to tourism industry, it takes the level of the tourism industry to a whole new level where touris... ome into play while implementing Information Technology in tourism - the information about the tourist places, the kind of places people would like to live in, the type of technology to be used and many such factors (Baggio, 2006). Each one has an important role to play in tourism. Tourism is characterized into three different components: Transport Sector Accommodation Sector Attraction Sector Transport Sector Transport is a major contributor to the development of the tourism industry. Transport helps link the origin and the destination areas through some means of transport. This means of transport could be any moving vehicle. Transport includes many entities such as holiday makers, business travelers, relatives, travelers, and other such entities. Transport facilitates the movement of these entities from one place to another. Before setting out on a journey of any kind, every traveler makes sure which Transport Company has a good safety record (Vich-I-Martorell, 2002). To this effect, airplanes coaches and even taxis are equipped with good communication equipment. An airplane requires highly sophisticated and highly advanced technical instruments to ensure passenger safety. Today's airplane has this highly advanced technical instruments and flies with the help of modern information technology equipment. A deep understanding and detailed weather information, altitude information and other such small but important information is provided by Information Technology. This information is given to the pilot. Using this information the pilot can communicate with the ground control during emergencies. With information technology in place, it is easy for airplanes to communicate to any airport during emergencies. In-flight entertainment is also a product of information